Stem cell-derived cell cultures and organoids for protozoan parasite propagation and studying host–parasite interaction

Drug Discovery via Human-Derived Stem Cell Organoids

Patient-derived cell lines and animal models have proven invaluable for the understanding of human intestinal diseases and for drug development although both inherently comprise disadvantages and caveats. Many genetically determined intestinal diseases occur in specific tissue microenvironments that are not adequately modeled by monolayer cell culture. Likewise, animal models incompletely recap...

Translational applications of adult stem cell-derived organoids.

Adult stem cells from a variety of organs can be expanded long-term in vitro as three-dimensional organotypic structures termed organoids. These adult stem cell-derived organoids retain their organ identity and remain genetically stable over long periods of time. The ability to grow organoids from patient-derived healthy and diseased tissue allows for the study of organ development, tissue home...

Propagation of goat pox virus on monolayer cell cultures

Lung Organoids and Their Use To Study Cell-Cell Interaction

PURPOSE OF REVIEW The lung research field has pioneered the use of organoids for the study of cell-cell interactions. RECENT FINDINGS The use of organoids for airway basal cells is routine. However, the development of organoids for the other regions of the lung is still in its infancy. Such cultures usually rely on cell-cell interactions between the stem cells and a putative niche cell for th...

P70: Produce Neural Stem Cell from Neurosphere of Rat Adipose Derived Stem Cell

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